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A new biological approach to guided bone and tissue regeneration

Identifieur interne : 002786 ( Main/Exploration ); précédent : 002785; suivant : 002787

A new biological approach to guided bone and tissue regeneration

Auteurs : Marco Montanari [Italie] ; Michele Callea [Italie] ; Izzet Yavuz [Turquie] ; Michele Maglione [Italie]

Source :

RBID : ISTEX:759B457CC7FF22906846D8A7E988E81E1646823A

English descriptors

Abstract

The purpose of this study was to determine the potential of platelet-rich fibrin (PRF) membranes used for guided bone and tissue regeneration. A patient with insufficient alveolar ridge width in aesthetic zone was enrolled. The patient's blood was centrifuged to obtain PRF membranes. Autogenous bone graft was mixed with bovine hydroxyapatite, PRF particles and applied to fill the defect. Five PRF membranes were placed over the bone mix. After 4 months a cone-beam CT was performed to evaluate bone regeneration. The use of PRF as cover membrane permitted a rapid epithelisation and represented an effective barrier versus epithelial cell penetration. After 4 months the site appeared precociously healed and the bone volume increased. This new approach represents a predictable method of augmenting deficient alveolar ridges. Guided bone regeneration with PRF showed limitation compared with guided bone regeneration using collagen membrane in terms of bone gain. The association of collagen membrane and PRF could be a good association.

Url:
DOI: 10.1136/bcr-2012-008240


Affiliations:


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Le document en format XML

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<term>Aesthetic zone</term>
<term>Alveolar ridge width</term>
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<term>Anticoagulant</term>
<term>Autologous bone</term>
<term>Bone architecture</term>
<term>Bone defect</term>
<term>Bone gain</term>
<term>Bone regeneration</term>
<term>Bone volume</term>
<term>Bovine hydroxyapatite</term>
<term>Brin</term>
<term>Choukroun</term>
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<term>Dentistry</term>
<term>Dis</term>
<term>Dohan</term>
<term>Effective barrier</term>
<term>Endod</term>
<term>Epithelial</term>
<term>Epithelial cell penetration</term>
<term>Further permission</term>
<term>Gingival</term>
<term>Good health</term>
<term>Good maturation</term>
<term>Graft</term>
<term>Gure</term>
<term>Healing period</term>
<term>Hydroxyapatite</term>
<term>Implant</term>
<term>Incision</term>
<term>Lingual mucoperiosteal</term>
<term>Membrane</term>
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<term>Oral pathol</term>
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<term>Predictable method</term>
<term>Present study</term>
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<term>Radiol endod choukroun</term>
<term>Radiol endod dohan</term>
<term>Rapid epithelisation</term>
<term>Regeneration</term>
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<term>Bone architecture</term>
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<term>Bone gain</term>
<term>Bone regeneration</term>
<term>Bone volume</term>
<term>Bovine hydroxyapatite</term>
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<term>Choukroun</term>
<term>Collagen membrane</term>
<term>Dentistry</term>
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<term>Effective barrier</term>
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<term>Epithelial cell penetration</term>
<term>Further permission</term>
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<term>Good health</term>
<term>Good maturation</term>
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<term>Gure</term>
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<term>Special care</term>
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<div type="abstract">The purpose of this study was to determine the potential of platelet-rich fibrin (PRF) membranes used for guided bone and tissue regeneration. A patient with insufficient alveolar ridge width in aesthetic zone was enrolled. The patient's blood was centrifuged to obtain PRF membranes. Autogenous bone graft was mixed with bovine hydroxyapatite, PRF particles and applied to fill the defect. Five PRF membranes were placed over the bone mix. After 4 months a cone-beam CT was performed to evaluate bone regeneration. The use of PRF as cover membrane permitted a rapid epithelisation and represented an effective barrier versus epithelial cell penetration. After 4 months the site appeared precociously healed and the bone volume increased. This new approach represents a predictable method of augmenting deficient alveolar ridges. Guided bone regeneration with PRF showed limitation compared with guided bone regeneration using collagen membrane in terms of bone gain. The association of collagen membrane and PRF could be a good association.</div>
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